It provides rapid information on drug resistance that takes up to six weeks using standard methods, US scientists report in the journal, Nature Communications.
The bacteria emit a unique gas signature within 10 minutes of exposure to an inhaled antibiotic in rabbits.
TB infects 8.6m people each year worldwide and kills 1.3m, second only to HIV.
Early diagnosis and treatment are a priority in the global fight against TB, according to the World Health Organization.
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